化學性質
Zeocinisanantibioticinthebleomycinfamily.ItsmodeofactionistointercalateintotheDNAanddegradeit.TheZeocinresistancegeneencodesa13,665daltonprotein.ThisproteinconfersresistancetoZeocinbybindingtotheantibioticandpreventingitfrombindingDNA.Zeociniseffectiveonmostaerobiccellsandcanbeusedforselectioninmammaliancelllines,yeast,andbacteria.ForZeocintobeactive,thesaltconcentrationintheselectionmediamustbelessthan90mMNaCl.TheamountofZeocinrequiredforselectionwillvarywitheachcelltype.Contents&Storage
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